About
Biography
Christine Cotton was born on 27 April 1970 in France. She trained as a biostatistician and spent some 25 years running clinical trials for the pharmaceutical industry as the founder and director of Statitec, a French contract research organisation (CRO). Across her career she contributed the statistical work behind dozens of therapeutic-area trials, FDA submissions, and peer-reviewed studies on which she is a named co-author.
From early 2021 she turned her statistical expertise on the COVID-19 vaccine clinical trials themselves, producing a detailed Good Clinical Practice (GCP) critique of the Pfizer/BioNTech pivotal trial C4591001. Successive editions of the report grew from a 105-page English expertise in February 2022 to a 414-page English flagship report (December 2024) and a 432-page French edition (January 2025). She published a book — Tous vaccinés, tous protégés ? (2023) — testified before France's Parliamentary Office for Scientific & Technological Assessment (OPECST) on 5 April 2022, and gave 18 video interviews across French-language outlets.
She is now deceased. This archive preserves her work in both languages so it remains accessible regardless of what happens to her own website, christinecotton.com.
Curriculum Vitae
Her full CV — career history at Statitec, list of therapeutic areas, FDA submissions, and named publications — is captured in this archive as a separate page:
About this archive
This site is an independently maintained, bilingual preservation archive of Christine Cotton's published work. It exists because her website may not stay online indefinitely, and her work — whatever a reader makes of its conclusions — represents a significant body of public research and testimony that deserves to remain accessible.
What is preserved here:
- Captured text of her major works — the GCP critique editions, the OPECST presentation, the McCullough slides, the summary updates, and her English-language book.
- The full French original of every page from her site, plus English translations for the pages that existed only in French.
- The 18 video interviews with links to the originals (transcripts are an open task).
- The 231 external sources she cited, indexed and searchable.
What is not republished here, by deliberate choice: her GCP expertise reports, summaries, and book carry her explicit copyright notice. Those documents are kept locally for preservation but the site links to her own christinecotton.com URLs rather than redistributing the PDFs. Similarly, the third-party documents she cited (the Pfizer C4591001 protocol; the Rose & Crawford VAERS paper) link to their original publishers (NEJM and the regulations.gov docket).
This archive does not editorialise her conclusions. Her reports are her work; the translations of her French-only site pages are noted as archive translations (not her own English). For corrections or takedown requests, please contact the maintainer — see the footer of any page.
A note from Christine Cotton
Content note: discussion of suicide.
Her last public message was posted on her own X account, @StatChrisCotton:
X (formerly Twitter) may eventually remove individual posts or close inactive accounts. A local copy is preserved on the maintainer's machine outside the public repository per the copyright policy for her own writing; if the X link breaks, contact the archive maintainer.